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    Learn Bioinformatics From Scratch (Theory & Practical)

    BY
    Udemy

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    Online

    Fees

    ₹ 499 3099

    Quick Facts

    particular details
    Medium of instructions English
    Mode of learning Self study
    Mode of Delivery Video and Text Based

    Course and certificate fees

    Fees information
    ₹ 499  ₹3,099
    certificate availability

    Yes

    certificate providing authority

    Udemy

    The syllabus

    Module 1 Databases

    • Definition of Databases
    • Database Design
    • Knowledge Discovery
    • Biological Databases
    • Take Home Key Points
    • Practical -1: NCBI Nucleotide Database
    • Practical-2: Protein Databank (PDB)
    • Quiz 1
    • Assignment 1

    Module 2 Sequence Alignment

    • What is Sequence Alignment?
    • Some Important Terms
    • Types of Sequence Alignment
    • What is Algorithms?
    • Dot Matrix Algorithm; How Does It Work?
    • Dot Matrix Algorithm; How to Interpret The Results?
    • Dot Matrix Algorithm; Identification of Repeat Sequences
    • Dot Matrix Algorithm; Advantages Vs Disadvantages
    • Practical-3: DotMatcher for Qualitative Comparison of Sequence
    • Assignment 2
    • Dynamic Programming Method: How Does It Work?
    • How to Transform Scoring Matrix to Alignment?
    • Dynamic Programming; Some Important Terms to Understand
    • Comparison Between DotMatrix and Dynamic Programming
    • Practical-4: Global Pairwise Sequence Alignment Using DNA Sequences
    • Practical-5: Pairwise Sequence Alignment Using Protein
    • Practical-6: Local Pairwise Sequence
    • Assignment 3
    • Introduction to Database Searching; BLAST
    • Type of Algorithms
    • How Does Word Algorithm Work? (Part-1)
    • How Does Word Algorithm Work? (Part-2)
    • A Important Term For Word Algorithm
    • Important Statistical Values to Evaluate the BLAST Results
    • Different Type of BLAST Associated with NCBI Databases
    • Practical -7: How to Use BLAST Program
    • Assignment 4
    • Optional: How to Use PSI-BLAST
    • Multiple Sequence Alignment; An Introduction
    • Algorithms for Multiple Sequence Alignment
    • Progressive Sequence Alignment Algorithm
    • Tools for Multiple Sequence Alignment
    • Practical -8: How to Use CLUSTAL-W
    • Practical -9: How to Use T-COFFEE
    • Assignment 5
    • Quiz 2

    Section 3 : Genomic Bioinformatics

    • Introduction of Module 3
    • What is DNA?
    • Where Is Our DNA is Located?
    • What Is Role of DNA?
    • What Does Gene Have?
    • Algorithms for Gene Prediction-1
    • Algorithms for Gene Prediction-2
    • GC-Bias and Test Code; An Ab-initio Type of Algorithm
    • Introduction of Markov Model (Part-1)
    • Introduction of Markov Model (Part-2)
    • Machine Learning and Gene Prediction
    • Practical-10: Prediction of Prokaryotic Gene
    • Practical-10.1 Prediction of Prokaryotic Regulatory Elements
    • Practical-11 Prediction of Eukaryotic Gene
    • Assignment 6
    • Assignment 7
    • Quiz 3

    Module 4 : Structural Bioinformatics

    • What is Protein? (Part-1)
    • What is Protein? (Part-2)
    • Some Important Points
    • Role of Amino Acids in 3D Structure
    • Peptide Bond; A link between Amino Acids
    • Secondary Structures of Proteins
    • Double Bond like Character in Peptide Bond & Ramachandran Plot
    • Forces Stabilizing The Protein Structure
    • Practical 13: Visualization of Protein Structure in Pymol (Part-1)
    • Why Protein Structure Prediction is So Important?
    • Protein Secondary Structure Prediction Algorithms (Part-1)
    • Protein Secondary Structure Prediction Algorithms (Part-2)
    • Practical-15: Prediction of Globular Protein Secondary Structure
    • Assignment 8
    • Algorithm for Secondary Structure Prediction of Transmembrane Proteins
    • Practical-16: Prediction of Transmembrane Helix Secondary Structure
    • Assignment 9
    • 3D Structure Prediction Algorithms
    • Homology Based Algorithm (Part-1)
    • Homology Based Algorithm (Part-2)
    • Homology Based Algorithm (Part-3)
    • Homology Based Algorithm (Part-4)
    • Model Validation & Draw back of Homology Based Algorithm
    • Practical-17: Prediction of 3D structure Using Homology Modeling (Mdeller)
    • Assignment 10
    • Threading Algorithm for 3D Structure Prediction
    • Practical-18: Prediction of 3D structure Using Threading Technique (I-TASSER)
    • Assignment 11
    • (Optional) Practical-18.1: Use of InterPro
    • (Optional) Practical 20: How to Perform Docking easily Using Vina
    • (Optional) Practical-21: How to Analyze the Docking Data
    • (Optional) Practical 3: ZINC Database for Drug Searching
    • Quiz 4
    • (Very Important) Practical Learn How to Use Alpha-Fold
    • Update Another GOR-IV Server for Secondary Structure Predictions

    Module 4 : Evolutionary Bioinformatics

    • What is Evolution and Phylogenetics
    • Some Important Terms To Understand Phylogenetic Tree
    • Different Type of Phylogenetic Trees
    • Steps To Construct Phylogenetic Tree
    • Selection of Molecular Marker for Tree Construction
    • Alignment for Tree Construction
    • Evolutionary Model Selection
    • Methods To Construct Tree
    • Validation of Tree By Bootstrapping
    • Practical -19: Building Phylogenetic Tree
    • Assignment 12
    • Quiz 5

    Module 6 (Optional)

    • Practical-22: How to Install Linux in Window for Bioinformatics Analysis
    • Practical-23: How to Install Gromacs in Windows
    • Practical-24: How to Download Chemsketch
    • Practical-25: Ligand Drawing and Making of Ligand 3D Structure

    Instructors

    Dr Muhammad Dujana

    Dr Muhammad Dujana
    Instructor
    Freelancer

    Ph.D

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