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D-Amino acids are amino acids where the stereogenic carbon alpha to the amino group has the D-configuration.
For most naturally-occurring amino acids, this carbon has the L-configuration.
D-Amino acids are most occasionally found in nature as residues in proteins. They are formed from ribosomally-derived D-amino acid residues.
Diverse D-amino acids, such as D-serine, D-aspartate, D-alanine, and D-cysteine, are found in mammals. Physiological roles of these D-amino acids not only in the nervous system but also in the endocrine system are being gradually revealed.
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