There are many Career option after completing class 12th with Commerce. Here are some of the Career options you can choose as per your interest.

Charted Accountant

Company Secretary

You need to apply CA CPT Entrance exam for it.

The next options:
B com: Bcom is most considerable course for commerce student.

BBA: BBA is a professional degree which focuses on formulating administrative skills.

BBS: BBS particularises in imparting students with immense understanding of several domains of business world. The course aims to build up critical thinking and analyzing skills.

BMS: The Bachelor of Management Studies includes the study of business mathematics, managerial economics, business ethics and corporate social responsibility, human resource management.
To choose a Career totally depends on your interest.

Good Luck!