Dear aspirant,

No, you will not face any problem while registering for NEET UG entrance exam because if biology being a optional subject, because your subject combination is considered as PCMB. The eligibility criteria for the exam states that the candidate must have passed class 12th with minimum 50% marks in PCB plus English as an aggregate, from a recognised board of education. So, just check how much you score excluding maths. If you Satisfy the criteria, you can apply for the exam.
Hope this helps.

Hopefully this will help you.
Thank you.