Correct Answer: Despite

Solution : The correct answer is option 1.

Explanation:

The following definitions are provided for the words in the options:

Despite: Despite (used before a fact that makes a subsequent fact surprising).

- Whether: (used especially in question reporting and doubt-expressing) whether or not.

- In case: in a specific instance or circumstance.

Thoughts can be contrasted using although. A subordinating conjunction, such as after, as, before, if, since, that, even though, or even if, is used to link a subordinate clause to the main clause.