Hi Niketan,

Inbreeding depression is the phenomenon of reduced biological fitness problem in a specified population as a result of inbreeding, or breeding of similar or related individuals. Population's biological fitness refers to an organism's ability to survive and continue making its genetic material. Inbreeding depression is a result of population bottleneck. In general, the higher the genetic variation within a breeding population, the less likely it is prone to suffer from inbreeding depression.

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I hope this information helps you.

Good Luck!