Yes, you can apply .The basic eligibility for admission to any of the Bcom programs is mentioned below.

Candidates must pass in Higher Secondary School examination from a recognized educational board

They should have Maths and English as core subjects. (A few universities consider only English as a mandory subject for admission)

Minimum 50% marks are required at 10+2 level

Although, candidates from Science and Arts stream are also eligible to apply, those with Commerce stream are preferred

There is no work experience required for the course. However, students with work experience can also apply.

So, before applying for a particular university confirm about their eligibility criteria once.

Some good colleges for commerce are:

Hans Raj College, New DelhiMadras Christian CollegeR.A. Podar College of Commerce & Economics, Lovely Professional University, Hindu College, New DelhiK. J. Somaiya College of Arts and Commerce, MumbaiChrist University, BangaloreSt. Xaviers College, MumbaiNarsee Monjee College of Commerce and Economics, Mumbai , PunjabSymbiosis College of Arts and Commerce, PuneSt. Josephs College of Commerce, BangaloreShri Ram College of CommerceLady Shri Ram College for WomenLoyola College, Chennai